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PTO/SB/08 (2-92) 
Sheet 1 of 1 



Form PTO-1449 

INFORMATION DISCLOSURE CITATION 
IN AN APPLICATION 

several sheets if necessary) 



Docket Number 4414720001 10 



Application Number 09/%M$2\ 



Applicant 



H. Ralph SNODGRASS 



Filing Date May 23, 2001 



flTT 



Group Art Unit 1633 



30 



Mailing Date February 22, 2002 



HFH- 



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7) 
n 



m* 1 



COPY 



U.S. PATENT DOCUMENTS 



CO 

o 



Tl 

D 



Examiner 
Initials 


ReT 
No. 


Date 


Document No. 


Name 


Class 


Subclass 


Filing Date If 
Appropriate 




1. 


11/19/1996 


5,576,207 


Reid et al. 










2. 


09/22/1998 


5,811,297 


Gopal 









FOREIGN PATENT DOCUMENTS 



Examiner 
Initials 


Ref. 
No. 


Date 


Document No. 


Country 


Class 


Subclass 


Translation 
YES NO 






03/04/1999 


WO 99/10535 ai 


WIPO 










3. 












4. 


05/14/1999 


WO 99/23254 ai 


WTPO 












5. 


06/03/1999 


WO 99/27090 ai 


WIPO 












6. 


09/02/1999 


WO 99/44062 ai 


WIPO 












7. 


05/25/2000 


WO 00/29002 A2j 


WIPO 





















OTHER DOCUMENTS 



(including author, title, Date, Pertinent Pages, Etc.) 



Examiner 
Initials 


Ref. 
No. 


Title 




8. 


Flint, O.P. (1998). "Predicting In Vivo Toxicity," Toxicology in Vitro 12:591-595. 




9. 


Ling, V. and S. Neben. (1997). "In Vitro Differentiation of Embryonic Stem Cells: Immunophentypic 
Analysis of Cultured Embryoid Bodies," J. Cell. Physiology 171:104-1 15. 




10. 


Matsui et al. (1992) "Derivation of Pluripotential Embryonic Stem Cells from Murine Primordial 
Germ Cells in Culture," Cell 70:841-847. 




11. 


Seamark, R.F. (1994). "Progress and Emerging Problems in Livestock Transgenesis: A Summary 
Perspective," Reprod. Fertil. Dev. 6:653-657. 




12. 


Spielmann et al. (1997). "The Ebryonic Stem Cell Test, an In Vitro Embryotoxicity Test Using Two 
Permanent Mouse Cell Lines: 3T3 Fibroblasts and Embryonic Stem Cells," In Vitro Toxicology 
10(1):1 19-127. 



EXAMINER: 



7* 



L 



DATE CONSIDERED: 



EXAMINER: Initial if citation considered, whether or not the citation conforms with MPEP 609. Draw a line through the citation if not in 
conformance and not considered. Include a copy of this form with next communication to applicant. 



PTO/SB/ 08 (2-92) 
pa-664805 



Patent and Trademark Office; U.S. DEPARTMENT OF COMMERCE 




PTO/SB/08 (2-92) 
Sheet 1 of 1 



Form PTO- 1449 

INFORMATION DISCLOSURE CITATION 
IN AN APPLICATION 

(Use several sheets if necessary) 



DocketWmber 4414720001 10 



Application Number 09/864,621 



H. Ralph SNODGRASS 



Filing Date May 23, 2001 



Group Art Unit 



Mailing Date March 20, 2002 



RECEIVE D 



U.S. PATENT DOCUMENTS 



APR 1 

TECH CENTER 



20C2 

160C/2900 



Examiner 
Initials 


Ref. 
No. 


Date 


Document No. 


Name 


Class 


Subclass 


Filing Date If 
Appropriate 



















FOREIGN PATENT DOCUMENTS 



Examiner 
Initials 



Ref. 
No. 



Date 



Document No. 



Country 



Class 



Subclass 



Translation 
YES NO 



1. 



04/08/1998 0 834 575 A2, 3, bi Europe 



OTHER DOCUMENTS 



(including author, title, Date, Pertinent Pages, Etc.) 



Examiner 
Initials 



Ref. 
No. 



Title 



Communication Pursuant to Article 1 15( 21ERCL(JanuaE 
party concerning the patentability of the invention. 



Observ ations filed by a third 



EXAMINER: 



<7h\\\^U^ [JaP^ 1 DATE CONSIDERED: /2^f^3 



EXAMINER: Initial if citation considered, whether or not the citation conforms with MPEP 609. Draw a line through the citation if not in 
conformance and not considered. Include a copy of this form with next communication to applicant. 



PTO/SB/08 (2-92) 
pa-675264 



Patent and Trademark Office; U.S. DEPARTMENT OF COMMERCE